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Grafting of 18-Crown-6 Functionalization on Microcantilever Biosensor for Pb2+ Poisoning Detection

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Microcantilevers with surface functionalizations recently have provided the possibilities of chemimechnanical transductions for sensing applications. In this study, the 18-crown-6 was grafted onto the carboxyl-microcantilever as surface functionalization for Pb2+ detection. Microcantilever with 18-crown-6 functionalization exhibited the surface configurations of adequate wetting property, strong covalent immobilization and selective Pb2+ adsorption. Experimental results revealed that the 18-crown-6 functionalized microcantilever exhibited the excellent Pb2+ sensing performances with a high sensitivity of 42.1 nm/log[Pb2+], a low detection limit as well as a wide detectable regime ranging from 10−7 to 10−1 M.
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Document Type: Research Article

Publication date: December 1, 2008

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