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Biosynthesis of Hydroxyapatite Nanoparticles, Characterization for the Treatment of Prostate Cancer in Nursing Care

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Hydroxyapatite [Ca10(PO4)6(OH)2] is the one of the major inorganic constituents of natural bone, which has been broadly used in medical and biological applications. The present research work reports on the preparation of hydroxyapatite nanoparticles (HA NPs) via a green and eco-friendly approach based on the use of pectin. The crystalline size, purity and morphology of the as-fabricated HA NPs were studied by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, energy dispersive X-ray (EDAX) spectroscopic analysis and scanning electron microscopy (SEM), correspondingly. Further, cytotoxicity investigations showed a dose dependent cytotoxicity towards prostate cancer cells (PC3 cells). Overall, the results illustrated herein suggest that the as-developed HA NPs may offer prospects for the development of drugs for prostate cancer treatment in nursing care for children.
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Keywords: HYDROXYAPATITE; NANOPARTICLES; PROSTATE CANCER

Document Type: Research Article

Publication date: January 1, 2020

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  • Science of Advanced Materials (SAM) is an interdisciplinary peer-reviewed journal consolidating research activities in all aspects of advanced materials in the fields of science, engineering and medicine into a single and unique reference source. SAM provides the means for materials scientists, chemists, physicists, biologists, engineers, ceramicists, metallurgists, theoreticians and technocrats to publish original research articles as reviews with author's photo and short biography, full research articles and communications of important new scientific and technological findings, encompassing the fundamental and applied research in all latest aspects of advanced materials.
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