Skip to main content
padlock icon - secure page this page is secure

Barium and Fluorine Doped Synthetic Hydroxyapatite: Characterization and In-Vitro Bioactivity Analysis

Buy Article:

$106.65 + tax (Refund Policy)

We have successfully doped hydroxyapatite (HA) with barium (Ba2+) and fluoride (F) ions to furnish Ca10– x Ba x (PO4)6(OH)2– y F y , (where x = 0–1 and y = 1) by using microwave assisted wet precipitation method. The resulting powders were characterized by using X-ray diffraction (XRD), Fourier transform IR spectroscopy (FTIR), field-emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDX), Brunauer, Emmett and Teller (BET), and inductively coupled plasma optical emission spectrometry (ICP-OES) to study phase purity, particle morphology, elemental composition, specific surface area and in-vitro ion release. XRD analysis confirmed the formation of pure phase barium doped fluorine-hydroxyapatite with increased lattice parameters but with reduced degree of crystallinity. FESEM analysis confirmed the formation of spherical nanoparticles with homogenous distribution of elements with reduction in crystallite size when compared to HA, while BET results showed an increase in specific surface area upon increased degree of Ba doping. In-vitro bioactivity study carried out in SBF revealed that the incorporation of Ba2+ ions into HA structure lead to the faster release of Ca2+ ions resulting in faster formation of apatite layer.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics


Document Type: Research Article

Publication date: February 1, 2015

More about this publication?
  • Science of Advanced Materials (SAM) is an interdisciplinary peer-reviewed journal consolidating research activities in all aspects of advanced materials in the fields of science, engineering and medicine into a single and unique reference source. SAM provides the means for materials scientists, chemists, physicists, biologists, engineers, ceramicists, metallurgists, theoreticians and technocrats to publish original research articles as reviews with author's photo and short biography, full research articles and communications of important new scientific and technological findings, encompassing the fundamental and applied research in all latest aspects of advanced materials.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more