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Synthesis, Properties and Heating Characteristics of Bovine Serum Albumin Coated Fe3O4 Magnetic Fluid for Magnetic Fluid Hyperthermia Application

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Bovine serum albumin (BSA) coated Fe3O4 magnetic fluid was synthesized by co-precipitation technique and its characteristics were investigated. The size of the nanoparticles was obtained as 8± 2 nm from transmission electron microscopy (TEM) measurement. Binding of BSA on surface of the Fe3O4 nanoparticles was confirmed by photoluminescence spectroscopy and zeta potential measurements. The magnetic nanoparticles showed superparamagnetic property with a saturation magnetization of 33.7 emu g–1. The heating characteristics of the magnetic fluid for magnetic fluid hyperthermia application were measured under the influence of an AC magnetic field amplitude of 2.9–3.5 kA m–1 and frequency of 130–300 kHz. The obtained maximum specific absorption rate (SAR) was 96.5 W g1for a magnetic field amplitude of 3.5 kA m–1 and frequency of 300 kHz.
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Keywords: CO-PRECIPITATION; MAGNETIC MATERIALS; MAGNETIC PROPERTIES; NANOSTRUCTURES

Document Type: Research Article

Publication date: September 1, 2013

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  • Science of Advanced Materials (SAM) is an interdisciplinary peer-reviewed journal consolidating research activities in all aspects of advanced materials in the fields of science, engineering and medicine into a single and unique reference source. SAM provides the means for materials scientists, chemists, physicists, biologists, engineers, ceramicists, metallurgists, theoreticians and technocrats to publish original research articles as reviews with author's photo and short biography, full research articles and communications of important new scientific and technological findings, encompassing the fundamental and applied research in all latest aspects of advanced materials.
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