Synthesis, Properties and Heating Characteristics of Bovine Serum Albumin Coated Fe3O4 Magnetic Fluid for Magnetic Fluid Hyperthermia Application
Bovine serum albumin (BSA) coated Fe3O4 magnetic fluid was synthesized by co-precipitation technique and its characteristics were investigated. The size of the nanoparticles was obtained as 8± 2 nm from transmission electron microscopy (TEM) measurement. Binding of BSA on surface of the Fe3O4 nanoparticles was confirmed by photoluminescence spectroscopy and zeta potential measurements. The magnetic nanoparticles showed superparamagnetic property with a saturation magnetization of 33.7 emu g–1. The heating characteristics of the magnetic fluid for magnetic fluid hyperthermia application were measured under the influence of an AC magnetic field amplitude of 2.9–3.5 kA m–1 and frequency of 130–300 kHz. The obtained maximum specific absorption rate (SAR) was 96.5 W g–1for a magnetic field amplitude of 3.5 kA m–1 and frequency of 300 kHz.
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Document Type: Research Article
Publication date: September 1, 2013
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