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Ginsenoside Rg3: Spectral Analysis and Sensitive Detection with Silver Nanoparticles Decorated Graphene

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Ginseng saponin Rg3 has attracted much attention in the past decades due to its excellent antitumor activity. Rg3 and related ginsenosides, as natural materials, have the potential to be the base and supporting materials for anticancer drugs. In the present study, infrared spectrum, mass spectrum, 1H nuclear magnetic resonance spectrum, 13C nuclear magnetic resonance spectra 1H–1H COSY, heteronuclear multiple-quantum coherence (HMQC) of loteprednol etabonate were applied and the results were interpreted. All the 1H NMR and 13C NMR chemical shifts were assigned by means of 1H–1H COSY\HMBC and HMQC. The molecular structure of ginsenoside Rg3 has been elucidated. By using silver nanoparticles decorated graphene, the sensitive detection of Rg3 was realized with electrochemical measurements. Electrochemical response was obtained in a wide range of concentration of ginseng saponin Rg3 (0.2–1.4 μmol/L) with the detection limit of 0.02 μmol/L.
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Document Type: Research Article

Publication date: November 1, 2012

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  • Science of Advanced Materials (SAM) is an interdisciplinary peer-reviewed journal consolidating research activities in all aspects of advanced materials in the fields of science, engineering and medicine into a single and unique reference source. SAM provides the means for materials scientists, chemists, physicists, biologists, engineers, ceramicists, metallurgists, theoreticians and technocrats to publish original research articles as reviews with author's photo and short biography, full research articles and communications of important new scientific and technological findings, encompassing the fundamental and applied research in all latest aspects of advanced materials.
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