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Antibacterial Activity of Graphene Oxide Nanosheets

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In this paper, we report on the antibacterial activity of graphene oxide (GO) nanosheets synthesized by the modified Hummers method. The as-prepared GO nanosheets were characterized using UV-vis spectroscopy, XRD, FT-IR spectroscopy, XPS, TEM and Raman spectroscopy analysis. The antibacterial activity of GO nanosheets towards Gram-negative bacteria, “Escherichia coli” and Gram-positive bacteria, “Streptococcus iniae,” was investigated by the colony counting method. The obtained results indicated that GO nanosheets were more effective towards Gram-positive bacteria. The mechanism underlying the antibacterial behavior of GO nanosheets involved the generation of reactive oxygen species, which was confirmed using the electron spin resonance technique coupled with spin trapping technique. These results proved that GO nanosheets can be used as a potential antibacterial agent in future applications of nanomedicine.
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Keywords: ANTIBACTERIAL ACTIVITY; ELECTRON SPIN RESONANCE SPECTROSCOPY; GRAPHENE OXIDE; REACTIVE OXYGEN SPECIES

Document Type: Research Article

Publication date: November 1, 2012

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  • Science of Advanced Materials (SAM) is an interdisciplinary peer-reviewed journal consolidating research activities in all aspects of advanced materials in the fields of science, engineering and medicine into a single and unique reference source. SAM provides the means for materials scientists, chemists, physicists, biologists, engineers, ceramicists, metallurgists, theoreticians and technocrats to publish original research articles as reviews with author's photo and short biography, full research articles and communications of important new scientific and technological findings, encompassing the fundamental and applied research in all latest aspects of advanced materials.
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