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Successful Treatment of a Case of Intracranial Infection Caused by Carbapenem-Resistant Klebsiella Pneumonia After Craniocerebral Operation in Patient with Severe Traumatic Brain Injury

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Klebsiella pneumoniae (KP) is one of the most common clinical drug-resistant bacteria, which is mainly related to the production of broad-spectrum beta lactamase and cephalosporin hydrolase. Carbapenems, an atypical beta lactam antibiotic, has been the most effective antibiotic for the treatment of bacterial infections caused by KP in hospital. However, with the extensive application of carbapenem antibiotics in clinic, many reports on carbapenem-resistant Klebsiella Pneumonia (CRKP) have appeared in many parts of the world. The CRKP could cause a higher mortality and morbidity. Here, we report a 26-year-old male patient with severe traumatic brain injury who underwent intracranial infection caused by CRKP after craniocerebral operation. He was successfully cured with a combination of emergency craniotomy, multidisciplinary consultation, effective nursing and strict quarantine measures. In the present report, we emphasize the effective nursing and strict quarantine measures, which contribute to the treatment of bacterial infections caused by KP.
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Document Type: Short Communication

Publication date: March 1, 2018

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  • Nanoscience and Nanotechnology Letters (NNL) is a multidisciplinary peer-reviewed journal consolidating nanoscale research activities in all disciplines of science, engineering and medicine into a single and unique reference source. NNL provides the means for scientists, engineers, medical experts and technocrats to publish original short research articles as communications/letters of important new scientific and technological findings, encompassing the fundamental and applied research in all disciplines of the physical sciences, engineering and medicine.
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