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Mechanical Properties and In Vitro Bioactivity of Nano-Fibrous Hydroxyapatite/Chitosan Composites

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Hydroxyapatite/chitosan (HA/CS) nano-fibrous composites with HA contents of 0–80 wt% were prepared by in situ hybridization. The hydroxyapatite nano-fibers with average diameter of about 3 nm and length of 20–60 nm homogeneously disperse in the chitosan matrix. The compressive strength of these nano-fibrous HA/CS composites increase with the increasing HA content and reached the highest values of 178 MPa. The results of in vitro tests in simulated body fluid solutions indicate that the HA/CS bio-composites have good biodegradability and bioactivity. All the results suggested that the HA/CS bio-composites are appropriate to be applied as bone substitute in bone tissue engineering.
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Keywords: BIO-COMPATIBILITY; HYDROXYAPATITE/CHITOSAN NANO-FIBROUS; IN VITRO

Document Type: Short Communication

Publication date: July 1, 2017

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  • Nanoscience and Nanotechnology Letters (NNL) is a multidisciplinary peer-reviewed journal consolidating nanoscale research activities in all disciplines of science, engineering and medicine into a single and unique reference source. NNL provides the means for scientists, engineers, medical experts and technocrats to publish original short research articles as communications/letters of important new scientific and technological findings, encompassing the fundamental and applied research in all disciplines of the physical sciences, engineering and medicine.
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