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Growth of Hydroxyapatite Coating on Polymer Microspheres

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Hydroxyapatite (HA) coated polymer microspheres was prepared by a two-step process under physiological temperature and pH value. A full coverage of plate-like structured HA coating was achieved on poly(lactic-co-glycolic acid) (PLGA) microspheres. Field emission scanning electron microscopy was employed to observe the surface morphology of microspheres before and after coating. Fourier Transform Infrared spectra and X-ray diffraction were used for the chemical groups and crystal structure examination. The HA coated PLGA microspheres have potential applications in controlled drug delivery systems.
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Keywords: BIOMIMETIC; DRUG DELIVERY; HYDROXYAPATITE COATING; POLY(LACTIC-CO-GLYCOLIC ACID) MICROSPHERES

Document Type: Short Communication

Publication date: August 1, 2011

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  • Nanoscience and Nanotechnology Letters (NNL) is a multidisciplinary peer-reviewed journal consolidating nanoscale research activities in all disciplines of science, engineering and medicine into a single and unique reference source. NNL provides the means for scientists, engineers, medical experts and technocrats to publish original short research articles as communications/letters of important new scientific and technological findings, encompassing the fundamental and applied research in all disciplines of the physical sciences, engineering and medicine.
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