Growth of Hydroxyapatite Coating on Polymer Microspheres
Hydroxyapatite (HA) coated polymer microspheres was prepared by a two-step process under physiological temperature and pH value. A full coverage of plate-like structured HA coating was achieved on poly(lactic-co-glycolic acid) (PLGA) microspheres. Field emission scanning electron microscopy was employed to observe the surface morphology of microspheres before and after coating. Fourier Transform Infrared spectra and X-ray diffraction were used for the chemical groups and crystal structure examination. The HA coated PLGA microspheres have potential applications in controlled drug delivery systems.
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Document Type: Short Communication
Publication date: August 1, 2011
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