Skip to main content
padlock icon - secure page this page is secure

Open Access Mechanisms underlying the action of self-assembling short-peptide nano-fiber gel scaffold materials in the aesthetic repair of burn wounds

Download Article:
 Download
(PDF 10,722.5 kb)
 
To study the mechanism of self-assembling short-peptide nano-fiber gel scaffolds on the aesthetic repair of burns. RADA16-1 assembled short-peptide nano-fiber gel scaffold was prepared using the ultrasonic method. Twenty female SD rats were randomly divided into two groups. Burn model was established using the electrical machinery method. The wound surface of the rats in the experimental group was coated with RADA16-1 and that of the rats in the control group was coated with NaCl. The degree of wound healing, hair follicle growth, hair growth length, and expression of bFGF and EGF were compared between the two groups. RADA16-1 fibers were broken into short fibers under the ultrasonic environment and then reorganized into gels. The degree of wound healing, hair follicle growth, hair growth length, and expression of bFGF and EGF in the experimental group were better than those in the control group. The assembly of short peptide nano-fiber gel scaffolds can effectively repair burn wounds.
No References for this article.
No Supplementary Data.
No Article Media
No Metrics

Keywords: Burn Wound; Short Peptide Nanofiber Gel Scaffold; Ultrasound

Document Type: Research Article

Affiliations: Department of Plastic and Burn Surgery, Tianjin First Center Hospital, Tianjin 300192, PR China

Publication date: March 1, 2020

More about this publication?
  • Materials Express is a peer-reviewed multidisciplinary journal reporting emerging researches on materials science, engineering, technology and biology. Cutting-edge researches on the synthesis, characterization, properties, and applications of a very wide range of materials are covered for broad readership; from physical sciences to life sciences. In particular, the journal aims to report advanced materials with interesting electronic, magnetic, optical, mechanical and catalytic properties for industrial applications.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more