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Influence of Process Parameters on Droplet Size of Nanoemulsion Formulated by Ultrasound Cavitation

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Cooking oil based food-grade nanoemulsion was formulated by ultrasonic emulsification method. Process of nanoemulsion formulation was optimized for parameters such as surfactant type, surfactant concentration and emulsification time to achieve minimum droplet diameter with high physical stability. Surfactant concentration plays important role in reducing emulsion droplet size. Emulsification time also minimizes droplet size during ultrasonic emulsification. Increase in surfactant concentration and emulsification time resulted in reduction of droplet diameter and increased stability of the emulsion. Tween80 minimized emulsion droplets better than Tween20. Stable mustard oil nanoemulsion (MT804) with droplet diameter 25 nm was formulated by ultrasonic emulsification for 30 min using Tween80 as surfactant. Droplet size of the emulsion correlates with optical transparency. Reduction in droplet size results in significant decrease in emulsion turbidity. Mustard oil nanoemulsion formulation MT804 was found to be optically transparent. The mustard oil nanoemulsion droplets were found to be spherical in morphology.
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Document Type: Research Article

Publication date: October 1, 2013

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  • Bionanoscience attempts to harness various functions of biological macromolecules and integrate them with engineering for technological applications. It is based on a bottom-up approach and encompasses structural biology, biomacromolecular engineering, material science, and engineering, extending the horizon of material science. The journal aims at publication of (i) Letters (ii) Reviews (3) Concepts (4) Rapid communications (5) Research papers (6) Book reviews (7) Conference announcements in the interface between chemistry, physics, biology, material science, and technology. The use of biological macromolecules as sensors, biomaterials, information storage devices, biomolecular arrays, molecular machines is significantly increasing. The traditional disciplines of chemistry, physics, and biology are overlapping and coalescing with nanoscale science and technology. Currently research in this area is scattered in different journals and this journal seeks to bring them under a single umbrella to ensure highest quality peer-reviewed research for rapid dissemination in areas that are in the forefront of science and technology which is witnessing phenomenal and accelerated growth.
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