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Antibacterial Effects In Vitro of Several Common Chinese Medicinal Herbs Upon Esherichia coli

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The in vitro antibacterial activities of a total of 8 ethanolic extracts from Chinese medicinal herbs were investigated by filter paper, double dilution and other methods against Esherichia coli. Diameter of inhibition zone (DIZ), minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined in the test. The results were as follows: These Chinese herbal medicines showed different degrees of inhibitory effects on tested bacteria. Extract of Scutellaria baicalensis exhibited the highest activity, Schisandra chinensis came second. The DIZ value of Scutellaria baicalensis was 14.6 mm, while Schisandra chinensis was 13.4 mm. The MIC value of Scutellaria baicalensis was low to 0.78125 mg/ml, the MBC value was 1.5625 mg/ml. The MIC value of Schisandra chinensis was 1.5625 mg/ml, the MBC value was 3.125 mg/ml. We found a certain parallel relationship between the size of inhibition circle and minimum inhibitory concentration, generally speaking, the herb which had a larger inhibition circle diameter showed a smaller MIC value, the herb with a smaller diameter showed a bigger MIC value.
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Keywords: ANTIBACTERIAL ACTIVITY; CHINESE MEDICINAL HERBS; ESHERICHIA COLI

Document Type: Research Article

Publication date: August 1, 2013

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  • Bionanoscience attempts to harness various functions of biological macromolecules and integrate them with engineering for technological applications. It is based on a bottom-up approach and encompasses structural biology, biomacromolecular engineering, material science, and engineering, extending the horizon of material science. The journal aims at publication of (i) Letters (ii) Reviews (3) Concepts (4) Rapid communications (5) Research papers (6) Book reviews (7) Conference announcements in the interface between chemistry, physics, biology, material science, and technology. The use of biological macromolecules as sensors, biomaterials, information storage devices, biomolecular arrays, molecular machines is significantly increasing. The traditional disciplines of chemistry, physics, and biology are overlapping and coalescing with nanoscale science and technology. Currently research in this area is scattered in different journals and this journal seeks to bring them under a single umbrella to ensure highest quality peer-reviewed research for rapid dissemination in areas that are in the forefront of science and technology which is witnessing phenomenal and accelerated growth.
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