Skip to main content
padlock icon - secure page this page is secure

In Vitro Cytotoxicity of Magnetic Spinel Nanoferrites (CoMgFe2O4) Against HepG2 Cells

Buy Article:

$105.00 + tax (Refund Policy)

Nanoscience and nanotechnology have fascinated new opportunities for the formation of advance materials for use in health as well as in medical applications. Due to unique chemical and physical properties, nanoparticles e.g., magnetic nanoferrites have been very useful and shown the potential application in nanomedicine. CoMgFe2O4 nanoparticles were synthesized by Sol–gel method. Morphological analysis of said nanoparticles (NPs) was confirmed by applying SEM and XRD. The exposure of spinel ferrites to Liver cancerous cells was examined by applying multidisciplinary techniques (MTT Assay and Inverted Microscopy). The exposure of CoMgFe2O4 to liver carcinoma at 10–80 μg/ml resulted in dose-dependent cellular viability loss and provoked cell death via apoptosis. In this study, experimental results have successfully demonstrated the translocation of magnetic ferrites nanoparticles in liver carcinoma (HepG2 cell model) and ensuring the significant toxicity. The study further proposed the forthcoming therapeutic use of these nanoferrites in the cancer study.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: CYTOTOXICITY; LIVER CARCINOMA; NANOFERRITES; REACTIVE OXYGEN SPECIES (ROS)

Document Type: Research Article

Publication date: February 1, 2018

More about this publication?
  • Journal of Nanoelectronics and Optoelectronics (JNO) is an international and cross-disciplinary peer reviewed journal to consolidate emerging experimental and theoretical research activities in the areas of nanoscale electronic and optoelectronic materials and devices into a single and unique reference source. JNO aims to facilitate the dissemination of interdisciplinary research results in the inter-related and converging fields of nanoelectronics and optoelectronics.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more