Fabrication of 3D Electrospun Polycaprolactone Sponge Incorporated with Pt@AuNPs for Biomedical Applications
Here, we report the synthesis of three-dimensional (3D) polycaprolactone (PCL) nanofiber incorporated with core-satellite platinum nanoparticles (PtNPs, 2–3 nm) coated gold nanospheres (AuNPs, 30 nm) via the simple lactic acid assisted self-assembly electrospinning technique.
The Pt-AuNPs nanoparticle in core-satellite form has been prepared by following solution based methods and characterized with TEM, HR-TEM, UV-Visible, and XRD spectroscopic techniques. The surface morphology and structural analysis of 3D nanofiber scaffolds have been performed with FTIR, TGA,
FESEM, and HR-TEM analysis techniques and shown the successful preparation of 3D electrospun fibrous structure composed of Pt-AuNPs loaded PCL (PCL@Pt-AuNPs) as a potential biomaterial for bone tissue engineering applications.
Keywords: 3D Scaffold; Bone Tissue Engineering; Core-Satellite Nanoparticles; Electro-Spinning; HR-TEM
Document Type: Research Article
Affiliations: 1: Division of Mechanical Design Engineering, Jeonbuk National University, Jeonju Jeonbuk, 561756, South Korea 2: Department of Medical Practicing, Woori Convalescent Hospital Jeonju, Jeonbuk, 54914, South Korea 3: Department of Bionanosystem Engineering, Jeonbuk National University, Jeonju, Jeonbuk, 561756, South Korea
Publication date: 01 July 2020
- Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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