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Size- and Morphology-Controlled Preparation of Surface-Modified Water-Dispersible Fullerene Nanoparticles for Bioapplications

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In this study, we investigated water-dispersible surface modification for size- and shape-controlled fullerene nanoparticles (C60P) based on a condensation reaction with di-amino alkane. This modification provided for water dispersibility of C60P and the capability for secondary modification as well. The resultant C60P particles have several useful physical properties: water-dispersibility for ease of injection; fluorescence for detection and quantification; and a characteristic morphology to assist identification. These properties will widely extend the applications of these particles, especially into the biological fields of bioimaging and drug delivery.
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Keywords: Fullerene Nanoparticles; Surface Modification; Water-Dispersibility

Document Type: Research Article

Affiliations: 1: Faculty of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan 2: Department of Materials Science and Engineering, Kitami Institute of Technology, Kitami 080-8507, Japan 3: Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand 4: School of Health Science, Kyushu University of Health and Welfare, Nobeoka 882-8508, Japan 5: Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto 1-7-1, Nagasaki 852-8102, Japan 6: Department of Applied Chemistry and Bioscience, Chitose Institute of Science and Technology, Chitose 066-8655, Japan

Publication date: May 1, 2020

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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