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Synthesis, Characterization and Anti-Biofilm Efficacy of Polypyrrole-Zinc Oxide Composites

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A nanocomposite of Polypyrrole (PPy) and zinc oxide (ZnO), termed as PPy-ZnO, was synthesized by two step route. In the first step, synthesis of PPy was carried out by chemical oxidative route. In the second step, the PPy-ZnO nanocomposite was synthesized under hydrothermal conditions. The as-synthesized PPy-ZnO nanocomposites were characterized using X-ray Diffraction (XRD), scanning electron microscopy (SEM), Fourier Transform Infra-red (FTIR) and Ultra violetvisible (UV-vis) spectroscopy to reveal the phase, morphology, chemical and optical properties. The physical and chemical characterizations confirmed presence of both PPy and ZnO phases in the nanocomposite. In the present work, antimicrobial activity of the PPy-ZnO nanocomposite against human pathogen Y. lipolytica has been investigated. Attempts have been made to reveal the influence of PPy percentage on the antimicrobial activity. Interestingly, all PPy-ZnO nanocomposites, irrespective of PPy percentage, showed 90 to 95% inhibited growth of Yarrowia lipolytica. The results obtained herein imply the potential of PPy-ZnO biofilm in inhibiting the growth of Y. lipolytica and thus preventing infections caused due to Y. lipolytica in humans.
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Keywords: Polypyrrole-ZnO; SEM; Y. lipolytica

Document Type: Research Article

Affiliations: 1: Centre for Advanced Studies in Material Science and Condensed Matter Physics, Department of Physics, Savitribai Phule Pune University, Pune 411007, India 2: Department of Microbiology, MES-Abasaheb Garware College (S.P. Pune University), Pune 411005, India

Publication date: April 1, 2020

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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