Bioinspired Carbon Quantum Dots: An Antibiofilm Agents
Carbon dots, very tiny carbon material with various surface passivations, have emerged as a new class of nanomaterials for various applications. Herein, we describe a simple, economical, and green approach for the synthesis of colloidal luminescent carbon dots (C-dots) by solvothermal
method from fruit juice of Citrus limetta, an abundantly available plant in Asian countries. The existence of C-dots was confirmed by X-ray Diffraction and High Resolution Transmission Electron Microscopy studies. The C-dots size was observed to be 2–4 nm. We further evaluated
the efficacy of C-dots to inhibit the attachment of Candida albicans MTCC 227, and biofilm formation on the polystyrene surfaces. The C-dots have effectively inhibited the attachment and formation of biofilm in Candida albicans at very low concentrations, which is hitherto unattempted.
The ability of C-dots to inhibit biofilm formation may contribute to diverse applications of C-dots in biomedical field.
Keywords: Anti-Biofilm; Carbon Dots; Citrus limetta; Morphology
Document Type: Research Article
Affiliations: 1: Centre for Materials for Electronics Technology (C-MET), Ministry of Electronics and Information Technology (MeitY), Government of India, Panchawati Off Pashan Road, Pune 411008, India 2: Department of Biotechnology, Savitribai Phule Pune University, Pune 411007, India
Publication date: 01 April 2019
- Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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