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Microwave Absorbing Fe3O4@mTiO2 Nanoparticles as an Intelligent Drug Carrier for Microwave-Triggered Synergistic Cancer Therapy

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Herein a novel multifunctional nanoplatform based on Fe3O4@mTiO2 (m was short for mesoporous) nanoparticles is developed for effective microwave-triggered synergistic cancer therapy. Fe3O4@mTiO2 nanoparticles employed in the study not only function as microwave absorbing agents but also as nanocarriers with a high drug loading efficiency. Fe3O4 core confers the system biocompatibility and cells targeting ability. Moreover, mTiO2 shell as drug carriers with a high drug loading efficiency and loading drug can controlled release on the microwave irradiation. By combining these capabilities, the multifunctional nanoparticles show an effective therapeutic efficiency toward the target cells.
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Keywords: Chemotherapy; [email protected]; Homogeneous Precipitation Method; Magnetic; Mesoporous; Microwave Thermal Therapy

Document Type: Research Article

Affiliations: Hunan Provincial Key Laboratory of Fine Ceramics and Powder Materials, Hunan University of Humanities, Science and Technology, Lou’di, 137400, Hunan Province, P. R. China

Publication date: August 1, 2017

More about this publication?
  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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