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Dynamic Manipulation of Charged Lipids in Model Membrane for Bio-Microarrays

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We describe the dynamic manipulation of the charged lipids in a confined geometry where two dispersive factors arising from the random diffusion-based Brownian motion and the field-induced drift of target lipids compete with each other. It is found that the lateral distribution of the target lipids is well controlled through a combined effect of an external electric field and the geometric restrictions by the confinement. The dynamic manipulation scheme for the charged lipids in twodimension would be useful for understanding the spatial organization of membrane components in a supported lipid membrane mimicking a real cell membrane and for producing membrane-based microarrays.
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Keywords: Bio-Microarray; Charged Lipids; Lateral Distribution; Supported Lipid Membrane

Document Type: Research Article

Affiliations: 1: School of Electrical Engineering #032, Seoul National University, Kwanak P. O. Box 34, Seoul 151-600, Republic of Korea 2: Department of Creative Convergence Engineering, School of Global Convergence Studies, Hanbat National University, Daejeon, 305-719, Republic of Korea 3: Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 130-701, Korea

Publication date: June 1, 2016

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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