Plasma Polymerization of 1,2-Diaminocyclohexane for Covalent Bonding of Bone Morphogenic Protein-2 on Titanium Surface
Among the bone morphogenic protein (BMP) family members, BMP-2 is a potent osteoinductive factor that plays key roles during bone formation. In this study, plasma polymerization of 1,2-diaminocyclohexane (DACH) was performed to immobilize the BMP-2 on Ti surface. The plasma polymerization
of DACH was carried out at a discharge power of 60 W and 100 W under a pressure of 10 mTorr for 90 sec. The BMP-2 was successfully immobilized on the DACH plasma treated Ti surface. The BMP-2 immobilized Ti surface showed the excellent cell differentiation. The results indicate that the DACH
plasma polymerized Ti surface has a potential for immobilization of biomolecules in bone tissue engineering.
Document Type: Research Article
Publication date: 01 August 2015
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