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New Method Expression of Protein Sequence and Its Application for Protein Sub-Cellular Localization Prediction

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Graphical representation of protein sequence is to provide intuitive overall graphs as well as useful insights for performing large-scale analysis. Some methods have been proposed to analyze the similarities/dissimilarities among different sequences. Here, we consider a novel 3D graphical representation of protein sequences. It is based on a substitution matrix and the frequency of the 20 common amino acids. According to this representation, we give a 2D distance formula to calculate the distance of different protein sequences for similarity analysis. Finally, the proposed method is used to predict protein cellular localization.

Document Type: Research Article

Publication date: 01 March 2014

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  • Journal of Computational and Theoretical Nanoscience is an international peer-reviewed journal with a wide-ranging coverage, consolidates research activities in all aspects of computational and theoretical nanoscience into a single reference source. This journal offers scientists and engineers peer-reviewed research papers in all aspects of computational and theoretical nanoscience and nanotechnology in chemistry, physics, materials science, engineering and biology to publish original full papers and timely state-of-the-art reviews and short communications encompassing the fundamental and applied research.
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