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Hydroxyapatite and Hydroxyapatite-Chitosan Composite from Crab Shell

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Natural crab shells (CS) is an important biological source of calcium. Like eggshell, CS also contains CaCO3 along with Chitin. CS becomes flexible when treated with dilute acetic acid and NaOH. Ca10(PO4)6(HO)2 or hydroxyapatite (HAp) layer is found to form on the surface of this flexible sheet by soaking it in K2HPO4(KHP) solution (0.25–0.3 mol%) for several days. HAp-Chitosan composite is also formed by immersing CS powder (250–300 μm) in KHP solution. Crab shell may be considered as an important biological source of HAp and the HAp-Chitosan composite which might be used for making scaffolds for tissue engineering and other applications.
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Keywords: BIOCERAMICS; BIOMATERIALS; CRAB SHELL; HYDROXYAPATITE; SCAFFOLDS

Document Type: Research Article

Publication date: December 1, 2013

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  • Journal of Biomaterials and Tissue Engineering (JBT) is an international peer-reviewed journal that covers all aspects of biomaterials, tissue engineering and regenerative medicine. The journal focuses on the broad spectrum of research topics including all types of biomaterials, their properties, bioimplants and medical devices, biofilms, bioimaging, BioMEMS/NEMS, biosensors, fibers, tissue scaffolds, tissue engineering and modeling, artificial organs, tissue interfaces, interactions between biomaterials, blood, cells, tissues, and organs, regenerative medicine and clinical performance.
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