Skip to main content
padlock icon - secure page this page is secure

The Intervention of Nanotechnology Against Epithelial Fungal Diseases

Buy Article:

$106.81 + tax (Refund Policy)

Fungal infections can attack epithelial tissues and, according to the immunological state of the patient, some of them invade deeper organs, becoming seriously life compromising. Besides, bloodstream and local infections associated with intravascular devices constitute a significant problem associated with increased mortality. Topical therapy is desirable since, in addition to targeting the site of infection, it reduces the risk of systemic side effects and increases patient compliance. In this review we describe the pros and cons of using nano-objects that being toxic in nature could be used to cover surfaces of medical devices, or can act as carriers for targeted delivery of antifungals to skin. Non-toxic nano-objects were also included because they improve the ocular delivery of antifungals, classically suffering from ineffective topical administration, difficult access for systemic medication or local invasive administration. The new preclinical developments of nanoparticulate agents against cutaneous and ocular mycosis are grouped in three main sections: (1) In vitro antifungal activity of metallic nanoparticles, (2) In vitro and in vivo antifungal activity of non metallic nanoparticles (3) Ocular delivery of non metallic nanoparticles.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics


Document Type: Review Article

Publication date: February 1, 2013

More about this publication?
  • Journal of Biomaterials and Tissue Engineering (JBT) is an international peer-reviewed journal that covers all aspects of biomaterials, tissue engineering and regenerative medicine. The journal focuses on the broad spectrum of research topics including all types of biomaterials, their properties, bioimplants and medical devices, biofilms, bioimaging, BioMEMS/NEMS, biosensors, fibers, tissue scaffolds, tissue engineering and modeling, artificial organs, tissue interfaces, interactions between biomaterials, blood, cells, tissues, and organs, regenerative medicine and clinical performance.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more