Skip to main content
padlock icon - secure page this page is secure

In Vivo Photodynamic Therapy and Magnetic Resonance Imaging of Cancer by TSPP-Coated Fe3O4 Nanoconjugates

Buy Article:

$106.81 + tax (Refund Policy)

In this paper, we present the preparation and characterization of organic dye-coated magnetic particles and its application as magnetic resonance imaging (MRI) and photodynamic therapy (PDT) agent. We have coated the surface of Fe3O4 magnetic nanoparticles by meso-tetra(4-sulfonatophenyl) porphyrin dihydrochloride (TSPP), a photosensitive drug used in PDT, which is capable of generating singlet oxygen on the surface of paramagnetic Fe3O4 nanoparticles when irradiated at 400 nm. While the MRI was performed with in vivo mice experiment along with proper irradiation and therapeutic effect was followed by using in-situ MRI technology. The resulting conjugate is a single particle platform that can simultaneously be used as a PDT therapeutic and MRI contrasting agent.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics


Document Type: Research Article

Publication date: December 1, 2010

More about this publication?
  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Terms & Conditions
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more