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Lipid Nanoparticles for Drug Delivery to the Brain: In Vivo Veritas

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The present article is not aimed at extensively reviewing the literature on lipid nanoparticles, already described in monographs of recent redaction, but will provide a compilation of in vivo evidences supporting their potentiality in overcoming the blood-brain barrier problem. The advantages of using lipid over polymer carriers will be also discussed.
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Keywords: BLOOD-BRAIN BARRIER (BBB); BRAIN DRUG DELIVERY; COLLOIDS; LIPID COLLOIDAL DISPERSIONS; NEUROVASCULAR UNIT (NVU); SOLID LIPID NANOPARTICLES (SLN)

Document Type: Review Article

Publication date: August 1, 2009

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  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
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