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A Chronic Viral Disease MERS-Corona Model Presenting with Optimal Control Strategy

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From 12 January to 31 May 2018, the National IHR Focal Point of The Kingdom of Saudi Arabia reported 75 laboratory confirmed cases of Middle East respiratory syndrome corona virus (MERS-CoV), including twentythree deaths reports. So it is the responsibility of WHO and all the developed countries to take action on time when an outbreak is detected. In this article the transmission of infection in human population is though by camel, which lead an epidemiological mathematical model. For this purpose, we find reproductive number R 0 and all the endemic points of the proposed model. The stability analysis are derived in the presence of reproductive number, while for global stability we introduced Lyapunov function. Here we try to control the spread of infection, for that order, we use η 1, η 2, η 3 control variables to maximize susceptible and recovered individuals, and trying to reduce infected individuals in number. Finally, numerical simulation is presented with and with out vaccination.

Keywords: ENDEMIC EQUILIBRIUM POINTS; GLOBAL STABILITY ANALYSIS; LOCAL; MATHEMATICAL MODEL; MERS-CORONA VIRUS; NUMERICAL SIMULATION; OPTIMAL CONTROL; R0BASIC REPRODUCTION NUMBER; STABILITY ANALYSIS

Document Type: Research Article

Publication date: 01 December 2018

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  • Journal of Advanced Physics is an interdisciplinary peer-reviewed journal consolidating research activities in all experimental and theoretical aspects of advanced physics. The journal aims in publishing articles of novel and frontier physics that merit the attention and interest of the whole physics community. JAP publishes review articles, full research articles, short communications of important new scientific and technological findings in all latest research aspects of physics.
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