The Role of Yacon Fructooligosaccharides on the Bile Acids Binding and Bile Salt Hydrolase Activities

The aim of this study was to describe the role of yacon tubers FOS-inulin with variation of boiling time (0, 30, 60, 90 minutes) on blood cholesterol levels, through the in vitro analysis of bile acid binding capacity by yacon tubers, and in vivo analysis. Fifty male hypercholesterolemia Wistar Rattus norvegicus were divided into four groups with treatment feeding (10% yacon FOS) and one group with standard feeding patterns, consumed for 45 days. Observed variables involved triglycerides and total cholesterol levels, free bile acids and amino acids of rat feces. Increasing boiling time of yacon tubers will decrease in the role of yacon FOS-inulin on binding bile acids and BSH activities through the reabsorption of bile acids in the enterohepatic cycle and decreasing taurine and glycine feces amino acids, thereby increasing total blood cholesterol levels.