Skip to main content
padlock icon - secure page this page is secure

Diagnosis of Dengue Hemorrhagic Fever Based on Laboratory Test of Serology and PCR from Suspected Patients in Hospital

Buy Article:

$106.34 + tax (Refund Policy)

Background: DHF (Dengue Hemorrhagic Fever) still become one of the health problems in Indonesia. Incidence rate of DHF was higher than 20 per 100.000 population. The clinical symptoms were not specific anymore. The aim of this study was to compare the sensitivity and specificity of DHF diagnosis between serology and PCR test. Method: This study was a descriptive observational using cross sectional approach. Twenty four patients of suspect DHF in a hospital in Semarang were recruited. Diagnosis was based on a rapid test which usually done in Hospital, and then the results were compared to PCR technique. Data were analyzed descriptively. Result: The result showed that all of the subjects (24 patients) had thrombocytopenia ≤150,000 cells/mm3. The number of males and females are equal 50%, the mean of age were 35.4 year old, and 36.4% of them were unemployed. This study found that IgM positivity were 50% (primer infection), and IgG were 37,5% (secondary infection). Based on PCR tests to the subjects, 35% positivity were found and 42,9% Den-3 strain were detected. One patient had mixed infection of Den-2 and Den-4. Conclusion: There was a difference in diagnosis between clinical symptoms and laboratory tests.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: Dengue Hemorrhagic Fever (DHF); IgM; PCR; Serology

Document Type: Research Article

Affiliations: 1: Public Health Faculty of Diponegoro University, Professor Soedarto, SH., Tembalang, Semarang, 50239, Indonesia 2: Science and Mathematic Faculty of Diponegoro University, Professor Soedarto, SH., Tembalang, Semarang, 50239, Indonesia

Publication date: April 1, 2017

More about this publication?
  • ADVANCED SCIENCE LETTERS is an international peer-reviewed journal with a very wide-ranging coverage, consolidates research activities in all areas of (1) Physical Sciences, (2) Biological Sciences, (3) Mathematical Sciences, (4) Engineering, (5) Computer and Information Sciences, and (6) Geosciences to publish original short communications, full research papers and timely brief (mini) reviews with authors photo and biography encompassing the basic and applied research and current developments in educational aspects of these scientific areas.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more