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Anti-Angiogenic Effect of Hydro-Alcoholic Extract of Alpinia galanga by Chorioallantoic Membrane Assay

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All tumors require vascular formation for their growth and survival. The formation of new blood vessel by cell migration, proliferation and endothelial sprouting called angiogenesis. It may provide the nutritions and oxygen to the tumor to encourage their growth. Many natural products are found and reported, which inhibit the angiogenesis. Alpinia galanga (Family-Zingiberaceae) is used in medicinal, culinary, and cosmetics for centuries. It is widely used as a spice in food as well as in traditional system of medicine, such as Ayurveda, Unani, Chinese and Thai folk medicine. This study focused to evaluate the anti-angiogenesis activity of Alpinia galanga extract using the chorioallantoic membrane (CAM) assay in chicken embryos.

Keywords: Antiangiogenic; Chorioallantoic; Proangiogenic; VEGF

Document Type: Research Article

Affiliations: 1: Department of Pharmaceutical Biotechnology, JSS College of Pharmacy, Ooty, JSS University, Mysuru 643001, India 2: Department of PhytoPharmacy and Pharmacognosy, JSS College of Pharmacy, Ooty, JSS University, Mysuru 643001, India

Publication date: March 1, 2017

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