Cholesterol Sensing Properties of Neodymium Doped NanoTiO2
A feasibility study of cholesterol sensing properties of cholesterol oxidase (COx) immobilized neodymium doped TiO2 films was carried out. Commercially available TiO2 nanopwoder of 25 nm diameter was used as starting material followed by doping with rare earth
metal (neodymium). Morphological observations revealed spherical shape particles with about 25 nm size. UV-Vis and FTIR results indicated changes in the band gap and various functional groups suitable for enzyme immobilization and neodymium doping. Thick films of these powders were screen
printed over a pre-printed gold electrode on glass epoxy substrate (SPE). COx was immobilized on the films by physical adsorption. Electrical properties of the film were studied at various cholesterol concentrations before and after immobilization, which indicated decrease in current after
immobilization. It is expected that current will decrease with increasing concentration of cholesterol due to its oxidative nature. It is realized Nd-doping results in sharp increase in sensitivity and varied linearly with cholesterol concentration when tested over the wide range of cholesterol
concentration i.e., 1 mg/dl to 200 mg/dl. The results of various analysis techniques and sensor characteristics are correlated.
Document Type: Research Article
Publication date: 01 July 2014
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