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Backward Extraction of Penicillin G Using AOT Reverse Micelles

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Backward extraction of penicillin G from an organic phase containing AOT reverse micelles into a fresh aqueous phase has been investigated. The extraction is influenced by the amount of penicillin G in the organic phase before backward extraction ( ), which relate to the initial amount of penicillin G before forward extraction (Paq.i.fw ), the salt concentration in the aqueous phase and the surfactant concentration. The results show that only a small amount of penicillin G were successfully transferred to a fresh aqueous phase from the organic phase without addition of any co-surfactant. Despite of successfully results in the forward extraction, the overall extraction yield of penicillin G is found much less to the initial amount of penicillin G before forward extraction (Paq.i.fw ) due to difficulties during the backward extraction process.
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Document Type: Research Article

Publication date: December 1, 2013

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  • ADVANCED SCIENCE LETTERS is an international peer-reviewed journal with a very wide-ranging coverage, consolidates research activities in all areas of (1) Physical Sciences, (2) Biological Sciences, (3) Mathematical Sciences, (4) Engineering, (5) Computer and Information Sciences, and (6) Geosciences to publish original short communications, full research papers and timely brief (mini) reviews with authors photo and biography encompassing the basic and applied research and current developments in educational aspects of these scientific areas.
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