Backward Extraction of Penicillin G Using AOT Reverse Micelles
Backward extraction of penicillin G from an organic phase containing AOT reverse micelles into a fresh aqueous phase has been investigated. The extraction is influenced by the amount of penicillin G in the organic phase before backward extraction (Por.i.bw ), which relate to the initial amount of penicillin G before forward extraction (Paq.i.fw ), the salt concentration in the aqueous phase and the surfactant concentration. The results show that only a small amount of penicillin G were successfully transferred to a fresh aqueous phase from the organic phase without addition of any co-surfactant. Despite of successfully results in the forward extraction, the overall extraction yield of penicillin G is found much less to the initial amount of penicillin G before forward extraction (Paq.i.fw ) due to difficulties during the backward extraction process.
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Document Type: Research Article
Publication date: December 1, 2013
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