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In Vitro Evaluation of Sr and Cu Doped Bioactive Glasses

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In this study, it was aimed to produce bioactive glasses (SiO2–CaO–P2O5–Na2O–CuO and SiO2–CaO–P2O5–Na2O–CuO–SrO) with the substitution of strontium and copper in different weight percentages. Thermal, and In Vitro biological properties of the glasses were studied and compared to each other. In Vitro simulated body fluid studies were performed to investigate the bioactivity of the produced glass samples. Scanning electron microscopy, X-ray diffraction, ultraviolet spectroscopy and inductively coupled plasma techniques were used to monitor changes in the glass surface and SBF composition. The results showed that all glasses favored precipitation of calcium phosphate layer when they were soaked in SBF; they can also deliver controlled doses of strontium and copper toward the SBF medium that is the determinant for bone tissue regeneration.
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Document Type: Research Article

Publication date: November 1, 2013

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  • ADVANCED SCIENCE LETTERS is an international peer-reviewed journal with a very wide-ranging coverage, consolidates research activities in all areas of (1) Physical Sciences, (2) Biological Sciences, (3) Mathematical Sciences, (4) Engineering, (5) Computer and Information Sciences, and (6) Geosciences to publish original short communications, full research papers and timely brief (mini) reviews with authors photo and biography encompassing the basic and applied research and current developments in educational aspects of these scientific areas.
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