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Numerical Study of a Three-Dimensional Modified Graft for the End-to-Side Anastomosis

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This study uses modified artificial blood grafts to assess improvements in anastomotic intimal hyperplasia, which can cause surgical failure because of abnormal blood flow, after coronary artery bypass surgery near the rigidwalled end-to-side anastomosis. We analyzed numerous phenomena of unsteady flow fields, such as secondary flow and recirculation regions using multiple three-dimensional artificial blood vessels bypass graft models. These models possessed multiple straight grafts with angles (20°, 45°, 60°, and 90°) and graft-chambers (with a radius of curvature 1 to 3.5 times greater than the radius of the host artery). Analysis results showed that the variation of wall shear stress was smaller in the cambered graft models than in the straight grafts. Additionally, the recirculation region near the anastomosis gradually narrows as the graft-angle decreases and the graftradius of the curvature in the downstream period increases. Regardless of the angle of the straight graft-model being reduced, the recirculation region issue cannot be resolved during this period. Only the cambered graft method can solve this issue. Therefore, we conclude that using a smaller graft angle and bigger graft radius of curvature is optimal for preventing intimal hyperplasia in the downstream period. Using a graft radius of curvature that is three times the radius of the host artery is ideal.
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Document Type: Research Article

Publication date: November 1, 2013

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  • ADVANCED SCIENCE LETTERS is an international peer-reviewed journal with a very wide-ranging coverage, consolidates research activities in all areas of (1) Physical Sciences, (2) Biological Sciences, (3) Mathematical Sciences, (4) Engineering, (5) Computer and Information Sciences, and (6) Geosciences to publish original short communications, full research papers and timely brief (mini) reviews with authors photo and biography encompassing the basic and applied research and current developments in educational aspects of these scientific areas.
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