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Comparing Biosequence Similarity Using the Hamiltonian Lattice Model and the Prospect for Two-Dimensional Codes

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Dot-plots have been widely used to explore the properties of various types of biosequences. Although traditional tools such as dot-plots have been proposed to solve the similarity problems between biosequences, determining the physical interpretation of dot-plot properties in sequence comparison still requires through exploration. This report suggests using the Hamiltonian lattice model to represent dot-plot qualities. The neighborhoods and overall information are evaluated for sequence structures. We demonstrate single-sequence graphical characteristics and sequence comparison characteristics to prove the feasibility of this novel method, and the disagreement between the present methods with the existing scoring methods is addressed for further investigations.
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Document Type: Research Article

Publication date: November 1, 2013

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  • ADVANCED SCIENCE LETTERS is an international peer-reviewed journal with a very wide-ranging coverage, consolidates research activities in all areas of (1) Physical Sciences, (2) Biological Sciences, (3) Mathematical Sciences, (4) Engineering, (5) Computer and Information Sciences, and (6) Geosciences to publish original short communications, full research papers and timely brief (mini) reviews with authors photo and biography encompassing the basic and applied research and current developments in educational aspects of these scientific areas.
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