Comparing Biosequence Similarity Using the Hamiltonian Lattice Model and the Prospect for Two-Dimensional Codes
Dot-plots have been widely used to explore the properties of various types of biosequences. Although traditional tools such as dot-plots have been proposed to solve the similarity problems between biosequences, determining the physical interpretation of dot-plot properties in sequence comparison still requires through exploration. This report suggests using the Hamiltonian lattice model to represent dot-plot qualities. The neighborhoods and overall information are evaluated for sequence structures. We demonstrate single-sequence graphical characteristics and sequence comparison characteristics to prove the feasibility of this novel method, and the disagreement between the present methods with the existing scoring methods is addressed for further investigations.
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Document Type: Research Article
Publication date: November 1, 2013
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