Microcontact Printing of (Bio)Molecules on Self-Assembled Monolayers of Zeolites L and Surface Mediated Drug Delivery
Self assembled monolayers (SAMs) of azide functionalized zeolite L crystals were prepared. Fluorescent dye molecules or bioactive peptides such as arginine-glycine-aspartic acid (RGD) were immobilized by acid catalyzed "Schmidt" reaction on the top side of an azide functionalized zeolite L monolayer using microcontact printing (mCP). The respective SAMs of RGD functionalized zeolites were used for cell adhesion experiments. Furthermore, fluorescence dye molecules (Hoechst 33342) loaded zeolites were used as nanocontainer to stain adhered cells on SAMs of zeolites by release of Hoechst 33342 dye molecules from the channels of zeolites L as a prove of principle to surface mediated drug delivery.
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Document Type: Research Article
Publication date: June 1, 2018
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- ADVANCED POROUS MATERIALS (APM) is an international peer-reviewed journal that publishes research activities on the fundamental aspects, synthesis, advanced characterization, structural properties, and multiple applications of all kinds of novel micro, meso-, nano- and macro-porous materials. APM also offers unique opportunity to report the energy and environmental related applications of advanced porous materials addressing significant environmental problems as a result of global climate changes. APM publishes reviews, full-length papers, and short communications, covering materials including zeolites, zeotypes, metal organic frameworks, layered materials, porous carbons, nitrides, metals, polymers, phosphides, chalcogenides, transition metal oxides, hydroxyapatite, gels, fibers, ceramics, glasses, membranes, and thermoelectric materials, mesoporous silica, amorphous and crystalline mesoporous metallosilicates, mesoporous hybrid materials, nanocomposites, porous organic molecules, graphenes, and open framework materials, and their applications in catalysis, sensing, adsorption, separation, drug delivery, magnetism, battery, supercapacitors, solar cells, nanodevices, and fine chemical synthesis.
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