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Comparison of Ferric Sulfate Combined Mineral Trioxide Aggregate Pulpotomy and Zinc Oxide Eugenol Pulpectomy of Primary Maxillary Incisors: An 18-month Randomized, Controlled Trial

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Purpose: The purpose of this study was to compare outcomes and survival of ferric sulfate with mineral trioxide aggregate (FS+MTA) pulpotomy and root canal therapy (RCT) in carious vital primary maxillary incisors. Methods: In this parallel group noninferiority trial, asymptomatic carious vital primary incisors with pulp exposure in healthy 18- to 46-month-olds were allocated randomly to receive FS+MTA pulpotomy or RCT between September 2010 and September 2012. Each incisor was classified into one of the following radiographic outcomes: N (incisor without pathologic change); Po (pathologic change present, follow-up recommended); Px (pathologic change present, extract.) Clinical findings and incisor survival were secondary outcomes. Results: Seventy subjects were enrolled with a total of 172 incisors. Twelve- and 18-month radiographic outcomes demonstrated no statistical difference between FS+MTA pulpotomy and RCT incisors for Px outcomes (P=0.38; odds ratio equals 0.60; 95 percent confidence interval equals 0.19 to 1.89; chi-square test). There was no statistical differences in clinical outcomes for FS+MTA pulpotomy and RCT at 12 and 18 months (P=0.51; Fisher's exact test) or survival for FS+MTA pulpotomy and RCT incisors (P=0.11; log-rank test). Conclusions: Ferric Sulfate with Mineral Trioxide Aggregate (FS+MTA) is an alternative to RCT for vital primary incisors.
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Keywords: FERRIC SULFATE; INCISORS; MINERAL TRIOXIDE AGGREGATE (MTA); PULPOTOMY; ROOT CANAL THERAPY

Document Type: Research Article

Affiliations: 1: Division Chief, Pediatric Dentistry, Janeway Children's Health and Rehabilitation Centre, and a clinical assistant professor, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada 2: Dentist-in-Chief, Department of Dentistry, The Hospital for Sick Children, and an associate professor, Dentistry, University of Toronto, in Toronto, ON, Canada 3: Staff Pediatric Dentist, Department of Dentistry, The Hospital for Sick Children, and an assistant professor, Dentistry, University of Toronto, in Toronto, ON, Canada 4: Clinical Research Project Coordinator, The Hospital for Sick Children, in Toronto, ON, Canada 5: Director of Clinics, Department of Dentistry, The Hospital for Sick Children, and an associate professor, Dentistry, University of Toronto, in Toronto, ON, Canada;, Email: [email protected]

Publication date: January 1, 2017

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  • Pediatric Dentistry is the official publication of the American Academy of Pediatric Dentistry, the American Board of Pediatric Dentistry and the College of Diplomates of the American Board of Pediatric Dentistry. It is published bi-monthly and is internationally recognized as the leading journal in the area of pediatric dentistry. The journal promotes the practice, education and research specifically related to the specialty of pediatric dentistry. This peer-reviewed journal features scientific articles, case reports and abstracts of current pediatric dental research.
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