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Open Access Developing a Performance Standard for Adequate Sanitization of Wire-Bar Lids

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The wire-bar lids on rodent cages are an integral part of the microenvironment and as such can impact rodent health and wellbeing. The Guide for the Care and Use of Laboratory Animals recommends changing wire-bar lids every other week but does not include a predetermined performance standard. To develop a sanitization performance standard, we evaluated the bacterial and other cellular burden of wire-bar lids over 4 wk. The results show no significant difference in ATP or bacterial burden over 3 wk of continuous use in conventional cages with standard rodent pelleted or high-fat diet or in IVC with an irradiated diet.

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Document Type: Research Article

Affiliations: 1: Laboratory Animal Sciences, AstraZeneca AB, Göteborg, Sweden 2: Laboratory Animal Sciences, AstraZeneca AB, Göteborg, Sweden. [email protected]

Publication date: 01 November 2016

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  • The Journal of the American Association for Laboratory Animal Science (JAALAS) serves as an official communication vehicle for the American Association for Laboratory Animal Science (AALAS). The journal includes a section of refereed articles and a section of AALAS association news. The mission of the refereed section of the journal is to disseminate high-quality, peer-reviewed information on animal biology, technology, facility operations, management, and compliance as relevant to the AALAS membership. JAALAS accepts research reports (data-based) or scholarly reports (literature-based), with the caveat that all articles, including solicited manuscripts, must include appropriate references and must undergo peer review.

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