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Open Access Metastatic Uterine Adenocarcinoma in an 8-year-old Gilt

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An 8-y-old gilt was evaluated after the onset of hemorrhagic perineal discharge. Uterine adenocarcinoma with metastases to the lungs and regional lymph nodes was diagnosed at necropsy. Tumor cells lacked expression of estrogen receptor α and progesterone receptor. This case represents the first reported uterine adenocarcinoma in a research pig and the first swine uterine neoplasia in which steroid hormone receptor expression was evaluated.

Document Type: Case Report

Affiliations: 1: University of North Carolina Department of Pathology and Laboratory Medicine, Chapel Hill, North Carolina, USA; NIEHS Cellular and Molecular Pathology Branch, Research Triangle Park, North Carolina, USA 2: University of North Carolina Department of Pathology and Laboratory Medicine, Chapel Hill, North Carolina, USA 3: NIEHS Cellular and Molecular Pathology Branch, Research Triangle Park, North Carolina, USA

Publication date: 01 November 2009

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  • The Journal of the American Association for Laboratory Animal Science (JAALAS) serves as an official communication vehicle for the American Association for Laboratory Animal Science (AALAS). The journal includes a section of refereed articles and a section of AALAS association news. The mission of the refereed section of the journal is to disseminate high-quality, peer-reviewed information on animal biology, technology, facility operations, management, and compliance as relevant to the AALAS membership. JAALAS accepts research reports (data-based) or scholarly reports (literature-based), with the caveat that all articles, including solicited manuscripts, must include appropriate references and must undergo peer review.

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