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Open Access Asthma in an Adult Female Vervet Monkey (Chlorocebus sabaeus)

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A 9-y-old, colony-bred, female vervet monkey (Chlorocebus sabaeus) presented with a 6-y history of open-mouth breathing, tachypnea, and sibilant wheezing. These symptoms did not significantly affect her activity or quality of life. Thoracic radiographs and results of bronchoalveolar lavage supported the diagnosis of asthma. Treatment comprising intramuscular prednisolone (tapered over 2 mo from twice daily to every other day), inhaled salmeterol–fluticasone (25 μg–250 μg per actuation twice daily) by mask, and a metered dose inhaler was successful in restoring a normal respiratory pattern. Despite the availability of several primate models of human asthma, this case represents the first report of spontaneous asthma in a NHP.

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Document Type: Case Report

Affiliations: 1: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies. [email protected] 2: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies; Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, Texas, USA 3: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies 4: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies; Behavioural Science Foundation, St Kitts, West Indies

Publication date: February 1, 2016

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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