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Open Access Systemic Coronaviral Disease in 5 Ferrets

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The prevalence of reported systemic coronaviral disease in ferrets (Mustela putorius furo), which resembles the dry form of feline infectious peritonitis, has been increasing in the literature since its initial diagnosis and characterization approximately 10 y ago. Here we describe the clinical signs, pathologic findings, and diagnosis by immunohistochemistry using an FIPV3-70 monoclonal antibody of systemic coronaviral disease in 5 ferrets, 2 of which were strictly laboratory-housed; the remaining 3 were referred from veterinary private practices. This case report illustrates the importance of considering FRSCV infection as a differential diagnosis in young, debilitated ferrets with abdominal masses and other supporting clinical signs.

Document Type: Case Report

Affiliations: 1: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA 2: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, SNBL USA, Everett, Washington, USA 3: Littleton Animal Hospital, Littleton, Massachusetts, USA 4: Northwest ZooPath, Monroe, Washington, USA 5: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. [email protected]

Publication date: 01 December 2015

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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