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Open Access A Structured Light-based System for Scanning Subcutaneous Tumors in Laboratory Animals

Tumor size or volume is often the primary endpoint in preclinical efficacy studies of anticancer drugs. Efficient and accurate measurement of such tumors is crucial to rapid evaluation of novel drug candidates. Currently available techniques for acquiring high-throughput data on tumor volume are time-consuming and prone to various inaccuracies and errors. The laser-scanning technology we describe here provides a convenient, high-throughput system for tumor measurement that reduces interoperator variability and bias while providing automated data collection, processing and analysis.

Document Type: Research Article

Publication date: 01 June 2008

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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