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Results From the NACC Uniform Data Set Neuropsychological Battery Crosswalk Study

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Introduction:

Four new nonproprietary tests were recommended for use in the National Alzheimer’s Coordinating Center’s Uniform Data Set Neuropsychological Battery. These tests are similar to previous tests but also allow for continuity of longitudinal data collection and wide dissemination among research collaborators.

Methods:

A Crosswalk Study was conducted in early 2014 to assess the correlation between each set of new and previous tests. Tests with good correlation were equated using equipercentile equating. The resulting conversion tables allow scores on the new tests to be converted to equivalent scores on the previous tests.

Results:

All pairs of tests had good correlation (ρ=0.68 to 0.78). Learning effects were detected for Logical Memory only. Confidence intervals were narrow at each point estimate, and prediction accuracy was high.

Discussion:

The recommended new tests are well correlated with the previous tests. The equipercentile equating method produced conversion tables that provide a useful reference for clinicians and researchers.
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Keywords: Alzheimer disease; cognitive impairment; longitudinal; neuropsychology; test equating

Document Type: Research Article

Affiliations: 1: National Alzheimer’s Coordinating Center 2: Department of Neurology, Oregon Health & Science University, Portland, OR, Department of Neurology, University of Michigan, Ann Arbor, MI 3: National Alzheimer’s Coordinating Center, Departments of Biostatistics 4: National Alzheimer’s Coordinating Center, Epidemiology, University of Washington, Seattle, WA 5: Epidemiology, University of Washington, Seattle, WA 6: Department of Psychiatry and Behavioral Sciences, Cognitive Neurology and Alzheimer’s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL

Publication date: April 1, 2016

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