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Publisher: Wolters Kluwer

Volume 121, Number 5, 18 August 2017

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Response by Veerman et al to Letter Regarding Article, “The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity”
pp. e21-e21(1)
Authors: Veerman, Christiaan C.; Wilders, Ronald; Wilde, Arthur A.; Coronel, Ruben; Remme, Carol Ann; Verkerk, Arie O.; Bezzina, Connie R.

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In This Issue
pp. 469-469(1)
Author: Williams, Ruth

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Meet the First Authors
pp. 470-471(2)

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Allele-Specific Gene Silencing
pp. 480-482(3)
Author: Nattel, Stanley

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When High Throughput Meets Mechanistic Studies
pp. 483-485(3)
Author: Heidecker, Bettina

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Besides Imprinting
pp. 486-487(2)
Author: Uchida, Shizuka

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Training for Success
pp. 488-489(2)
Author: Correll, Robert N.

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Michael Potente
pp. 490-491(2)
Author: Williams, Ruth

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Cardiovascular Research in Germany
pp. 492-495(4)
Authors: Heusch, Gerd; Eschenhagen, Thomas; Dimmeler, Stefanie

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Large Animal Model Efficacy Testing Is Needed Prior to Launch of a Stem Cell Clinical Trial
pp. 496-498(3)
Authors: Epstein, Stephen E.; Luger, Dror; Lipinski, Michael J.

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Application of PCSK9 Inhibitors in Practice
pp. 499-501(3)
Authors: Kaufman, Tina M.; Duell, P. Barton; Purnell, Jonathan Q.; Wójcik, Cezary; Fazio, Sergio; Shapiro, Michael D.

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Genetic Deletion of NADPH Oxidase 1 Rescues Microvascular Function in Mice With Metabolic Disease
pp. 502-511(10)
Authors: Thompson, Jennifer A.; Larion, Sebastian; Mintz, James D.; Belin de Chantemèle, Eric J.; Fulton, David J.; Stepp, David W.

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ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype
pp. 512-524(13)
Authors: Liu, Renjing; Lo, Lisa; Lay, Angelina J.; Zhao, Yang; Ting, Ka Ka; Robertson, Elizabeth N.; Sherrah, Andrew G.; Jarrah, Sorour; Li, Haibo; Zhou, Zhaoxiong; Hambly, Brett D.; Richmond, David R.; Jeremy, Richmond W.; Bannon, Paul G.; Vadas, Mathew A.; Gamble, Jennifer R.

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Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene (RYR2)
pp. 525-536(12)
Authors: Bongianino, Rossana; Denegri, Marco; Mazzanti, Andrea; Lodola, Francesco; Vollero, Alessandra; Boncompagni, Simona; Fasciano, Silvia; Rizzo, Giulia; Mangione, Damiano; Barbaro, Serena; Di Fonso, Alessia; Napolitano, Carlo; Auricchio, Alberto; Protasi, Feliciano; Priori, Silvia G.

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The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity
pp. 537-548(12)
Authors: Veerman, Christiaan C.; Podliesna, Svitlana; Tadros, Rafik; Lodder, Elisabeth M.; Mengarelli, Isabella; de Jonge, Berend; Beekman, Leander; Barc, Julien; Wilders, Ronald; Wilde, Arthur A.M.; Boukens, Bastiaan J.; Coronel, Ruben; Verkerk, Arie O.; Remme, Carol Ann; Bezzina, Connie R.

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Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice
pp. 549-563(15)
Authors: Qiao, Yun; Lipovsky, Catherine; Hicks, Stephanie; Bhatnagar, Somya; Li, Gang; Khandekar, Aditi; Guzy, Robert; Woo, Kel Vin; Nichols, Colin G.; Efimov, Igor R.; Rentschler, Stacey

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Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension
pp. 564-574(11)
Authors: Dikalova, Anna E.; Itani, Hana A.; Nazarewicz, Rafal R.; McMaster, William G.; Flynn, Charles R.; Uzhachenko, Roman; Fessel, Joshua P.; Gamboa, Jorge L.; Harrison, David G.; Dikalov, Sergey I.

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Inhibition of the Cardiac Fibroblast–Enriched lncRNA Meg3 Prevents Cardiac Fibrosis and Diastolic Dysfunction
pp. 575-583(9)
Authors: Piccoli, Maria-Teresa; Gupta, Shashi Kumar; Viereck, Janika; Foinquinos, Ariana; Samolovac, Sabine; Kramer, Freya Luise; Garg, Ankita; Remke, Janet; Zimmer, Karina; Batkai, Sandor; Thum, Thomas

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