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Effect of Prophylactic Medication on Associated Dizziness and Motion Sickness in Migraine

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Objective:

To determine the efficacy of prophylactic medications for migraine in reducing associated dizziness and motion sickness.

Study Design:

Multicenter prospective observational study.

Setting:

Nationwide 9 Dizziness Clinics in South Korea.Patients:

One hundred thirty-eight patients who required a preventive medication for migraine accompanied by dizziness and motion sickness.


Intervention:

At least one of the prophylactic medications was prescribed among the beta-blockers, calcium channel blockers, tricyclic antidepressants, and antiepileptic drugs.

Main Outcome Measure:

For 3 months from the index visit, the patients had monthly assessments of the headache (frequency and duration), dizziness handicap inventory, University of California Los Angeles dizziness questionnaire, vertigo symptom scale, and motion sickness score.Results:

The prophylactic medications significantly improved the headache profiles, all three parameters of dizziness (dizziness handicap inventory, University of California Los Angeles dizziness questionnaire, and vertigo symptom scale), and severity of motion sickness (p < 0.001).
Conclusion:

The prophylactic medication for migraine also improves associated dizziness and motion sickness as well as the headaches.
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Keywords: Dizziness; Migraine; Prophylactic medication; Vertigo

Document Type: Research Article

Affiliations: 1: Department of Neurology, Chonnam National University Medical School, Gwangju 2: Department of Neurology, Chungnam National University School of Medicine, Daejeon 3: Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine 4: Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Research Administration Team, Seoul National University Bundang Hospital, Seongnam 5: Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine, and Biomedical Research Institute, Busan 6: Department of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan 7: Department of Neurology, Chonbuk National University School of Medicine, Jeonju 8: Department of Neurology, Ulsan University Hospital, Ulsan 9: Department of Neurology, Chosun University College of Medicine, Gwangju 10: Department of Neurology, Eulji University School of Medicine, Seoul, Republic of Korea

Publication date: January 1, 2018

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