@article {Jenkins:2016:1064-8011:2174, title = "Neuromuscular Adaptations After 2 and 4 Weeks of 80% Versus 30% 1 Repetition Maximum Resistance Training to Failure", journal = "Journal of Strength and Conditioning Research", parent_itemid = "infobike://wk/jsc", publishercode ="wk", year = "2016", volume = "30", number = "8", publication date ="2016-08-01T00:00:00", pages = "2174-2185", itemtype = "ARTICLE", issn = "1064-8011", url = "https://www.ingentaconnect.com/content/wk/jsc/2016/00000030/00000008/art00013", doi = "doi:10.1519/JSC.0000000000001308", keyword = "electromyography, mechanomyography, muscle strength, resistance training intensity, load, muscle hypertrophy, interpolated twitch", author = "Jenkins, Nathaniel D.M. and Housh, Terry J. and Buckner, Samuel L. and Bergstrom, Haley C. and Cochrane, Kristen C. and Hill, Ethan C. and Smith, Cory M. and Schmidt, Richard J. and Johnson, Glen O. and Cramer, Joel T.", abstract = "Jenkins, NDM, Housh, TJ, Buckner, SL, Bergstrom, HC, Cochrane, KC, Hill, EC, Smith, CM, Schmidt, RJ, Johnson, GO, and Cramer, JT. Neuromuscular adaptations after 2 and 4 weeks of 80% versus 30% 1 repetition maximum resistance training to failure. J Strength Cond Res 30(8): 21742185, 2016The purpose of this study was to investigate the hypertrophic, strength, and neuromuscular adaptations to 2 and 4 weeks of resistance training at 80 vs. 30% 1 repetition maximum (1RM) in untrained men. Fifteen untrained men (mean \textpm SD; age = 21.7 \textpm 2.4 years; weight = 84.7 \textpm 23.5 kg) were randomly assigned to either a high-load (n = 7) or low-load (n = 8) resistance training group and completed forearm flexion resistance training to failure 3 times per week for 4 weeks. Forearm flexor muscle thickness (MT) and echo intensity, maximal voluntary isometric (MVIC) and 1RM strength, and the electromyographic, mechanomyographic (MMG), and percent voluntary activation (%VA) responses at 10100% of MVIC were determined at baseline, 2, and 4 weeks of training. The MT increased from baseline (2.9 \textpm 0.1 cm) to week 2 (3.0 \textpm 0.1 cm) and to week 4 (3.1 \textpm 0.1 cm) for the 80 and 30% 1RM groups. MVIC increased from week 2 (121.5 \textpm 19.1 Nm) to week 4 (138.6 \textpm 22.1 Nm) and 1RM increased from baseline (16.7 \textpm 1.6 kg) to weeks 2 and 4 (19.2 \textpm 1.9 and 20.5 \textpm 1.8 kg) in the 80% 1RM group only. The MMG amplitude at 80 and 90% MVIC decreased from baseline to week 4, and %VA increased at 20 and 30% MVIC for both groups. Resistance training to failure at 80 vs. 30% 1RM elicited similar muscle hypertrophy, but only 80% 1RM increased muscle strength. However, these disparate strength adaptations were difficult to explain with neuromuscular adaptations because they were subtle and similar for the 80 and 30% 1RM groups.", }