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Presumed Larsen syndrome in a child: a case with a 12-year follow-up

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Larsen syndrome (OMIM 150250) was first described in 1950 as an entity characterized by distinct facial features and dislocations of the multiple large joint, and cleft palate, hearing loss, and spinal abnormalities were occasionally observed. The prevalence of Larsen syndrome is estimated to be one in 100 000 live births . Management of multiple large-joint dislocations often proves difficult with a tendency toward recurrence, particularly if a patient has complete dislocation of the knee .We treated a boy with the clinical phenotype of Larsen syndrome using 10 orthopedic procedures, but failed to achieve a satisfactory outcome.The aim of this report is to review the surgical course and report results of surgical treatments for this patient with 12 years of follow-up
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Keywords: Children; Larsen syndrome; long-term follow-up

Document Type: Miscellaneous

Affiliations: Department of Pediatric Orthopaedics, Hunan Children’s Hospital, The Pediatric Academy of University of South China, Changsha City, China

Publication date: May 1, 2015

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