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Anterior Chamber Angle and Trabecular Meshwork Measurements Made by Fourier-domain Optical Coherence Tomography in Healthy White Children

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To obtain anterior chamber angle and trabecular meshwork (TM) measurements by Fourier-domain optical coherence tomography (FD-OCT) in a population of healthy white children.

Materials and Methods:

This was a cross-sectional study examining 409 right eyes of 409 children. Trabecular-iris angle (TIA) and TM length and area were measured by FD-OCT (RTVue 100) in the nasal and temporal quadrants to analyze correlations between angle or TM measurements and age, sex, and refractive error.


Mean participant age was 10.5±3.4 years (range, 3 to 18 y); 51% were boys. Mean spherical error was 0.56±2.4 D (range, −9 to +7.5 D). TIA could be measured in 99%, whereas TM measurements could only be made in 83%. Mean TIA was 43.1±10.0 degrees (range, 16 to 76 degrees). No differences were observed in angle width according to sex (P=0.299; t test). TIA was correlated with age (R=0.204; P<0.001) and with spherical error (R=−0.457; P<0.001). Mean TM length was 530±106 μm (range, 299 to 891 μm) and mean TM area was 0.065±0.021 mm2 (range, 0.030 to 0.180 mm2). No correlation was observed between TM metrics and age, sex or refractive error (R<0.08; P≥0.172).


FD-OCT proved useful for the noninvasive measurement of TIA and TM metrics in children. Spherical error was the main determinant of TIA.
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Keywords: anterior chamber angle; children; glaucoma; optical coherence tomography; trabecular meshwork

Document Type: Research Article

Affiliations: 1: Departments of Ophthalmology, Centro Internacional de Oftalmología Avanzada, Madrid 2: Centro Internacional de Oftalmología Avanzada, Madrid 3: Departments of Ophthalmology 4: Preventive Medicine, Hospital Universitario Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC) 5: Centro Internacional de Oftalmología Avanzada, Madrid, Department of Ophthalmology, Universidad de Extremadura, Badajoz, Spain

Publication date: September 1, 2017

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