@article {Sondermeyer:2016:0891-3668:166,
title = "Epidemiology of Pediatric Coccidioidomycosis in California, 20002012",
journal = "The Pediatric Infectious Disease Journal",
parent_itemid = "infobike://wk/inf",
publishercode ="wk",
year = "2016",
volume = "35",
number = "2",
publication date ="2016-02-01T00:00:00",
pages = "166-171",
itemtype = "ARTICLE",
issn = "0891-3668",
eissn = "1532-0987",
url = "https://www.ingentaconnect.com/content/wk/inf/2016/00000035/00000002/art00014",
doi = "doi:10.1097/INF.0000000000000952",
keyword = "fungus, epidemiology, coccidioidomycosis, valley fever, pediatric",
author = "Sondermeyer, Gail L. and Lee, Lauren A. and Gilliss, Debra and McCarty, James M. and Vugia, Duc J.",
abstract = "
Background:
Reported coccidioidomycosis cases have increased in the southwestern US since 2000. However, there are few publications on pediatric coccidioidomycosis. We sought to describe the epidemiology of coccidioidomycosis in the California pediatric population during
20002012. 
Methods:
We reviewed surveillance and hospitalization datasets for years 20002012 and death datasets for years 20002010 to identify coccidioidomycosis-associated cases, hospitalizations and deaths in pediatric (17 years old) California
residents. We calculated rates and described demographic characteristics of cases and hospitalized patients and, using Poisson regression, calculated bivariate relative risks to identify potential demographic risk factors. We identified immunocompromising conditions associated with hospitalization
and death and calculated hospitalization charges. 
Results:
We identified 3453 cases, 1301 hospitalizations and 11 deaths associated with coccidioidomycosis in the California pediatric population. During 20002012, annual case and hospitalized patient rates increased
and were highest in males, those in the 1217 age group, and residents of the California endemic region. Compared with White children, African-American children were significantly more likely to be hospitalized (relative risk = 1.4, P = 0.01). Approximately 12.0% of those hospitalized
and 27% of those who died had an immunocompromising condition. Hospitalized patients accrued $149 million in total hospital charges. 
Conclusions:
Similar to recent increases among adults, reported pediatric coccidioidomycosis cases and hospitalizations have increased
in California since 2000, disproportionately affecting certain demographic groups. The burden of coccidioidomycosis among California children emphasizes the need for more awareness and research into this reemerging fungal disease in endemic and nonendemic areas.",
}