Skip to main content
padlock icon - secure page this page is secure

Opioid-induced hyperalgesia: where are we now?

Buy Article:

$52.00 + tax (Refund Policy)

Purpose of review

Patients receiving chronic opioid treatment who develop paradoxical pain sensations, as well as worsening existing pain, can be diagnosed as suffering from opioid-induced hyperalgesia (OIH). As the worldwide population expands so too does the proportion of patients who experience pain that requires a strong opioid. Recognizing the symptoms of OIH and optimizing the use of morphine in the hospital setting is imperative. This review focuses on clinical data relating to evidence of OIH at the bedside and the novel techniques employed by healthcare providers in order to improve the heightened pain sensations experienced by susceptible patients.

Recent findings

An increasing number of randomized prospective controlled trials report worsening patient pain following high-dose opioid treatment. Patient case reports support the premise that OIH is a clinical reality. According to recent literature, for those individuals who develop paradoxical pain sensations upon chronic opioid therapy, the most successful course of action involves a multidisciplinary attack that usually comprises early diagnosis, opioid switching and adjunct therapies.Summary

Looking to the future, improved clinicianâ–“patient communication, advanced diagnostic techniques and a refinement of prescribed adjunct pharmacotherapies will offer the most successful multimodal pain management approach to the problem of OIH.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: clinical data; opioid; opioid-induced hyperalgesia; worsening pain

Document Type: Research Article

Publication date: June 1, 2015

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more