In Egypt, there is a paucity of biomarker data on aflatoxin (AF) exposure. The study assessed the level and frequency of breast milk AFM 1 as a biomarker of maternal exposure. Breast milk samples were collected from a selected group of 388 Egyptian lactating mothers of children attending the New El-Qalyub Hospital, Qalyubiyah governorate, Egypt, during May–September 2003. Following aflatoxin extraction, AFM 1 levels were assessed by high-performance liquid chromatography (HPLC) with fluorescence detection. Approximately 36% of mothers tested positive for AFM 1 (median 13.5pgml −1 , interquartile range (IQR) 10.27–21.43). Non-working status ( p =0.018, odds ratio (OR)=2.87), obesity ( p =0.004, OR=3.01), high corn oil consumption ( p =0.002, OR=2.21), number of children (>1) ( p =0.025, OR=1.99), and early lactation stage (
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Document Type: Research Article
Department of Food Toxicology and Contaminants, National Research Centre, Dokki, Egypt
Molecular Epidemiology Unit, Centre for Epidemiology and Biostatistics, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds LS2 9JT, UK
Department of Clinical Nutrition
July 1, 2006
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